ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
Current issue Archive About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank


 
1/2020
vol. 85
 
Share:
Share:
more
 
 
Head and neck radiology
abstract:
Original paper

Altered intrinsic brain activity and regional cerebral blood flow in patients with chronic neck and shoulder pain

Xi Yue
1
,
Yong Du
1

1.
Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China
© Pol J Radiol 2020; 85: e155-e162
Online publish date: 2020/03/16
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Purpose
To identify the changes of intrinsic brain activity and regional cerebral blood flow in patients with chronic neck and shoulder pain (CNSP) by using amplitude of low-frequency fluctuation (ALFF) analysis and arterial spin labelling study.

Material and methods
In total, 28 CNSP patients and 25 age-matched and sex-matched healthy controls (HCs) partici­pated in the study. Resting-state functional magnetic resonance imaging (rs-fMRI) and arterial spin labelling (ASL) MRI were acquired. Correlations between ALFF and cerebral blood flow (CBF) were analysed. Subsequently, the differences in ALFF and CBF were compared in the two groups. Finally, the visual analogue scale (VAS) was also assessed in the CNSP group.

Results
Compared with HCs, CNSP patients showed significantly abnormal ALFF and CBF in several brain regions, including the cerebellum posterior lobe, middle orbitofrontal gyrus, medial superior frontal gyrus, middle temporal gyrus, precuneus, cingulate gyrus, middle occipital gyrus, middle frontal gyrus, postcentral gyrus, precentral gyrus, and superior parietal gyrus. Correlation analysis showed that the ALFF value of the medial superior frontal gyrus posi­tively correlated with the VAS score. However, no correlation was found between the CBF values and the VAS score.

Conclusions
The altered ALFF and CBF values in CNSP patients were observed in different pain-related brain regions that were involved in pain modulation and perception. The combination of rs-fMRI and ASL MRI might provide complementary information for increasing our understanding of the neuropathology in CNSP.

keywords:

chronic neck and shoulder pain, cervical spondylotic radiculopathy, resting-state functional magnetic resonance imaging, amplitude of low-frequency fluctuation, arterial spin labelling, cerebral blood flow

 
Quick links
© 2020 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe