ISSN: 1899-0967
Polish Journal of Radiology
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vol. 83
Original paper

Computed tomography-guided catheter drainage with ozone in management of pyogenic liver abscess tomography-guided catheter drainage with ozone in management of pyogenic liver abscess

Xiao-Xue Xu, Chuan Liu, Lang Wang, Yang Li, Han-Feng Yang, Yong Du, Chuan Zhang, Bing Li

© Pol J Radiol 2018; 83: e275-e279
Online publish date: 2018/06/12
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To compare the treatment efficacy of percutaneous catheter drainage alone to catheter drainage combined with ozone in the management of pyogenic liver abscess (PLA).

Material and methods
This prospective study included 85 patients diagnosed with PLA. All patients were randomly divided into two groups: catheter drainage alone (Group I); catheter drainage combined with ozone (Group II). Drainage was considered successful when: 1) the abscess cavities were completely drained, and 2) clinical symptoms were resolved. Kruskall-Wallis nonparametric test was used to compare the success rates, length of stay (LOS), and need of further surgery. A value of p < 0.05 was considered significant for all statistical analyses.

In all the patients’ percutaneous catheters were placed successfully under the guidance of computed tomo­graphy. All of the patients in Group I (43; 50.6%) were treated with percutaneous catheter drainage alone, while the patients in Group II (42; 49.4%) were treated with PCD combined with ozone. The success rates of Group I and II were 81% and 94%, respectively (p < 0.05). The duration of fever as well as LOS was longer for Group I when compared with Group II (p <0.05).

Catheter drainage combined with ozone is an effective and safe treatment in PLA.


pyogenic liver abscess, catheter drainage, interventional radiology, ozone

Dulku G, Mohan G, Samuelson S, et al. Percutaneous aspiration versus catheter drainage of liver abscess: A retrospective review. Australas Med J 2015; 8: 7-18.
Jun CH, Yoon JH, Wi JW, et al. Risk factors and clinical outcomes for spontaneous rupture of pyogenic liver abscess. J Dig Dis 2015; 16: 31-36.
Ahmed S, Chia CL, Junnarkar SP, et al. Percutaneous drainage for giant pyogenic liver abscess--is it safe and sufficient? Am J Surg 2016; 211: 95-101.
Lai KC, Cheng KS, Jeng LB, et al. Factors associated with treatment failure of percutaneous catheter drainage for pyogenic liver abscess in patients with hepatobiliary-pancreatic cancer. Am J Surg 2013; 205: 52-57.
Liao WI, Tsai SH, Yu CY, et al. Pyogenic liver abscess treated by percutaneous catheter drainage: MDCT measurement for treatment outcome. Eur J Radiol 2012; 81: 609-615.
Srivastava A, Yachha SK, Arora V, et al. Identification of high-risk group and therapeutic options in children with liver abscess. Eur J Pediatr 2012; 171: 33-41.
Thomas J, Turner SR, Nelson RC, et al. Postprocedure sepsis in imaging-guided percutaneous hepatic abscess drainage: how often does it occur? AJR Am J Roentgenol 2006; 186: 1419-1422.
Li B, Liu C, Li Y, et al. Computed tomography-guided catheter drainage with urokinase and ozone in management of empyema. World J Radiol 2017; 9: 212-216.
Andreula C. Ozone therapy. Neuroradiology 2011; 53: S207-S209.
Li B, Xu XX, Du Y, et al. CT-guided chemonucleolysis combined with psoas compartment block in lumbar disc herniation: a rando­mized controlled study. Pain Med 2014; 15: 1470-1476.
Re L, Rowen R, Travagli V. Ozone Therapy and Its Use in Medicine: Further Comments. Cardiology 2016; 136: 269.
Sharma N, Kaur H, Kalra N, et al. Complications of Catheter Drainage for Amoebic Liver Abscess. J Clin Exp Hepatol 2015; 5: 256-258.
Kusumoto K, Hamada A, Kusaka T, et al. A patient with sepsis and a gas-forming liver abscess caused by Clostridium perfringens treated with continuous perfusion drainage. Nihon Shokakibyo Gakkai Zasshi 2014; 111: 1416-1423.
Liu CH, Gervais DA, Hahn PF, et al. Percutaneous hepatic abscess drainage: do multiple abscesses or multiloculated abscesses preclude drainage or affect outcome? J Vasc Interv Radiol 2009; 20: 1059-1065.
Bari S, Sheikh KA, Malik AA, et al. Percutaneous aspiration versus open drainage of liver abscess in children. Pediatr Surg Int 2007; 23: 69-74.
Elvis AM, Ekta JS. Ozone therapy: A clinical review. J Nat Sci Biol Med 2011; 2: 66-70.
Gupta G, Mansi B. Ozone therapy in periodontics. J Med Life 2012; 5: 59-67.
Lo JZ, Leow JJ, Ng PL, et al. Predictors of therapy failure in a series of 741 adult pyogenic liver abscesses. J Hepatobiliary Pancreat Sci 2015; 22: 156-165.
Yu G, Liu X, Chen Z, et al. Ozone therapy could attenuate tubulointerstitial injury in adenine-induced CKD rats by mediating Nrf2 and NF-kappaB. Iran J Basic Med Sci 2016; 19: 1136-1143.
Takeuchi Y, Okabe H, Myojo S, et al. CT-guided drainage of a mediastinal pancreatic pseudocyst with a transhepatic transdiaphragmatic approach. Hepatogastroenterology 2002; 49: 271-272.
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