ISSN: 1899-0967
Polish Journal of Radiology
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2018
vol. 83
 
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abstract:
Original paper

Coronary age, based on coronary calcium measurement, is increased in patients with morbid obesity

Adam Lemanowicz, Marcin Białecki, Waldemar Leszczyński, Mateusz Hawrył

© Pol J Radiol 2018; 83: e415-e420
Online publish date: 2018/09/05
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Purpose
Obesity is a well-known of risk factor for atherosclerosis. However, recently an “obesity paradox” has been discussed, which is considered as a protective effect of obesity on the development coronary artery disease (CAD). An aim of the study was to investigate the risk of CAD in morbidly obese patients using coronary artery calcium measurement.

Material and methods
Fifty-one patients with morbid obesity (BMI ≥ 40 kg/m2) and thirty controls were scanned to determine the amount of coronary artery calcification (CAC), which was expressed as calcium score (CS) and coronary age (CA). The control group consisted of patients scanned for the clinical suspicion of CAD, who did not fulfil the criteria of obesity.

Results
Mean BMI of obese patients and controls was 47.3 and 26.5, respectively (p < 0.0001). Arterial hypertension, dyslipidaemia, and smoking were more frequent in the control group than in the obesity group (p < 0.02). The prevalence of CAC was higher in the obesity group (53% vs. 23%, p < 0.01). The groups did not differ regarding CS and CA. However, the difference between coronary age and metrical age was higher in obese patients than in controls (+5.6 vs. –4.8 years, respectively, p < 0.005).

Conclusions
Patients with morbid obesity present an increased risk of CAD that is reflected by the difference between their coronary age and metrical age.

keywords:

morbid obesity, coronary age, calcium score, atherosclerosis

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