Gallium-67 SPECT-CT for the evaluation of head and neck: preliminary study on maximum standardised uptake value in lesions, and in the parotid and submandibular glands

Purpose
The aim of this study was to investigate the gallium-67 (⁶⁷Ga) single-photon emission-computed tomography (SPECT-CT) for the evaluation of head and neck, especially maximum standardised uptake value (SUV_max) in lesions, and in the parotid and submandibular glands.

Material and methods
Fourteen patients with head and neck lesions who underwent SPECT-CT at 72 hours after injection of ⁶⁷Ga were included in this study. The ⁶⁷Ga SPECT-CT parameters SUV_max were compared between the parotid glands and submandibular glands. Statistical analyses for the SUV_max were performed by Mann-Whitney U test. A p value lower than 0.05 was considered as statistically significant.

Results
Of all 14 patients, ⁶⁷Ga SPECT-CT was positive for two cases (one malignant lymphoma and one osteomye­litis). The SUV_max for malignant lymphoma and osteomyelitis were 11.21 and 10.95, respectively. Furthermore, SUV_max for parotid glands and submandibular glands of all patients were 4.86 ± 1.89 and 4.64 ± 1.64, respectively (p = 0.694).

Conclusions
This study investigated the ⁶⁷Ga SPECT-CT for the evaluation of head and neck, especially SUV_max of lesions, and the parotid and submandibular glands. ⁶⁷Ga SPECT-CT may be an effective technique for the evaluation of maxillofacial lesions.