ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
Current issue Archive About the journal Editorial board Abstracting and indexing Contact Instructions for authors
SCImago Journal & Country Rank

vol. 83
Original paper

Magnetic resonance diffusion-weighted imaging in diagnostics of primary fallopian tube carcinoma – is it useful?

Laretta Grabowska-Derlatka, Wojciech Szeszkowski, Jacek Sieńko, Paweł Derlatka

© Pol J Radiol 2018; 83: e161-e165
Online publish date: 2018/04/20
View full text
Get citation
JabRef, Mendeley
Papers, Reference Manager, RefWorks, Zotero
Primary fallopian tube carcinoma (PFTC) is the rarest form of female genital malignancy. The imaging applied for suspected adnexal masses includes transvaginal ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), but the vast majority of PFTC is recognised intraoperatively.

Material and methods
The study group consisted of seven women with postoperatively histopathological diagnosis of PFTC. To recognise characteristic findings for PFTC, retrospective analysis of preoperative MRI was performed. All patients underwent MRI of the pelvis and abdomen using a 1.5T MR system. Based on the results of the above imaging, suspected adnexal masses were recognised. MRI protocol contained T2-weighted images, fat-suppressed T2-weighted, T2-TIRM, DW EPI, pre- and postcontrast dynamic 3D T1 GRE in transverse orientation, with diffusion weightings of 0, 50, 100, 150, 200, 400, 800, and 1200 s/mm2. Regions of interest were outlined by a radiologist, who documented the character of adnexal masses on diffusion-weighted (DW) images and apparent diffusion coefficient (ADC) maps.

In all seven patients with PFTC unilateral tumour was found. On all DW images (with β values of 0, 50, 100, 150, 200, 400, 800, and 1200 s/mm2) the mean signal intensities of solid parts of tumour were significantly higher than the mean signal intensities of normal ovarian tissue (p = 0.0001). There were no statistically significant differences between eight β values applied for ADC calculations.

Preoperative diagnostics of PFTC is difficult and mainly based on morphological features. Previous research did not show characteristics of PFTC in post-contrast dynamic imaging. In our material a clear increasing of signal intensity in DW imaging occurred independently of the β value.


primary fallopian tube carcinoma (PFTC), magnetic resonance diffusion-weighted imaging, ADC values of fallopian tube tumours

Alvarado-Cabrero I, Stolnicu S, Kiyokawa T, et al. Carcinoma of the fallopian tube: results of a multi-institutional retrospective analysis of 127 patients with evaluation of staging and prognostic factors. Ann Diagn Pathol 2013; 17: 159-164.
Nik NN, Vang R, Shih I-M, et al. Origin and pathogenesis of pelvic (ovarian, tubal, and primary peritoneal) serous carcinoma. Annu Rev Pathol Mech Dis 2014; 9: 27-45.
Dietl J. Revisiting the pathogenesis of ovarian cancer: the central role of the fallopian tube. Arch Gynecol Obstet 2013; 289: 241-246.
Seidman JD, Zhao P, Yemelyanova A. “Primary peritoneal” high-grade serous carcinoma is very likely metastatic from serous tubal intraepithelial carcinoma: assessing the new paradigm of ovarian and pelvic serous carcinogenesis and its implications for screening for ovarian cancer. Gynecol Oncol 2011; 120: 470-473.
Gadducci A, Landoni F, Sartori E, et al. Analysis of treatment failures and survival of patients with fallopian tube carcinoma: a cooperation task force (CTF) study. Gynecol Oncol 2001; 81: 150-159.
Pectasides D, Pectasides E, Economopoulos T. Fallopian tube carcinoma: a review. Oncologist 2006; 11: 906-912.
Kyriazi S, Collins DJ, Morgan VA, et al. Diffusion-weighted imaging of peritoneal disease for noninvasive staging of advanced ovarian cancer. Radiographics 2010; 30: 1269-1285.
Shaaban AM, Rezvani M. Imaging of primary fallopian tube carcinoma. Abdom Imaging 2013; 38: 608-618.
Rezvani M, Shaaban AM. Fallopian tube disease in the nonpregnant patient. Radiographics 2011; 31: 527-548.
Hosokawa C, Tsubakimoto M, Inoue Y, et al. Bilateral primary fallopian tube carcinoma: findings on sequential MRI. Am J Roentgenol 2006; 186: 1046-1050.
Gomes FV, Dias JL, Lucas R, et al. Primary fallopian tube carcinoma: review of MR imaging findings. Insights Imaging 2015; 6: 431-439.
Ma FH, Cai SQ, Qiang JW, et al. MRI for differentiating primary fallopian tube carcinoma from epithelial ovarian cancer. J Magn Reson Imaging 2015; 42: 42-47.
Sala E, Kataoka MY, Priest AN, et al. Advanced ovarian cancer: multiparametric MR imaging demonstrates response and metastasis-specific effects. Radiology 2012; 263: 149-159.
Lindgren A, Anttila M, Rautiainen S, et al. Primary and metastatic ovarian cancer: characterization by 3.01 diffusion-weighted MRI. Eur Radiol 2017; 27: 4002-4012.
Quick links
© 2018 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.
PayU - płatności internetowe