ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
SCImago Journal & Country Rank
 
1/2021
vol. 86
 
Share:
Share:
more
 
 
Cardiovascular radiology
abstract:
Original paper

Magnetic resonance imaging assessment of cerebral small vessel disease intensification in patients with severe aortic valve stenosis

Jakub Chrostowski
1
,
Marcin Majos
2
,
Andrzej Walczak
3
,
Mariusz Wachowski
1
,
Agata Majos
1

1.
Department of Radiological and Isotopic Diagnosis and Therapy, Medical University of Lodz, Poland
2.
Department of Radiology and Diagnostic Imaging, Medical University of Lodz, Poland
3.
Department of Cardiac Surgery, Medical University of Lodz, Poland
Pol J Radiol 2021; 86: e564-573
Online publish date: 2021/09/27
View full text
Get citation
ENW
EndNote
BIB
JabRef, Mendeley
RIS
Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
 
Introduction
To assess the prevalence of the neuroradiological indices of cerebral small vessel disease (CSVD) in patients with severe aortic valve stenosis (AS) in magnetic resonance imaging (MRI).

Material and methods
34 patients (age 60-90 years, 17 women and 17 men) with severe AS and 50 healthy controls (age 61-85 years, 29 women and 21 men) underwent MRI brain examinations, which were analysed for the neuroradiological indices of CSVD: hyperintensities in periventricular white matter (PVWM) and deep white matter (DWM), enlarged perivascular spaces (ePVS), lacunar strokes, and cerebral microbleeds (CMBs).

Results
PVWM hyperintensities were found in 46% of volunteers and was significantly lower (p = 0.027), corresponding to AS patients (80%), the density of lesions was higher in the AS group than in controls (p = 0.019). DWM hyperintensities were found more often in AS patients (76%) than in controls (66%) (p = 0.303), but the densities were similar in both groups. Lacunar strokes were found in 35% of AS patients and 16% of controls (p = 0.042). The average number of lacunar strokes per person was 0.9 in the AS group and 0.3 in the controls (p = 0.035). The AS group showed higher variance in the number of strokes: SD = 1.96 vs. SD = 1.06 in controls. Both prevalence and density of the ePVS and CMBs did not differ significantly between the groups.

Conclusions
Neuroradiological indices of the vascular disease do not provide an unequivocal clue to the pathogenesis of CSVD in patients with severe AS. Most observations imply that CSVD is primarily a consequence of cerebral hypoperfusion caused by AS.

keywords:

aortic stenosis, cerebral small vessel disease, lacunar stroke, perivascular spaces, cerebral microbleed, white matter hyperintensities




Quick links
© 2021 Termedia Sp. z o.o. All rights reserved.
Developed by Bentus.