ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
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1/2021
vol. 86
 
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Gastrointestinal and abdominal radiology
abstract:
Original paper

Optimizing diagnostic imaging data using LI-RADS and the Likert scale in patients with hepatocellular carcinoma

Kholoud Morad
1
,
Amr F. Moustafa
1
,
Amal M. Refaat
1
,
Ahmed AbdEllatif
1
,
Mohammed S. ElAzab
1

1.
National Cancer Institute, Cairo University, Cairo, Egypt
Pol J Radiol 2021; 86: e557-e563
Online publish date: 2021/09/23
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Introduction
The study aimed to compare the diagnostic performance of the Liver Imaging Reporting and Data System (LI-RADS), which incorporates fixed criteria, and the Likert scale (LS), which mainly depends on an overall impression in liver lesion diagnosis.

Material and methods
Diagnostic data of 110 hepatic nodules in 103 high-risk patients for hepatocellular carcinoma (HCC) were included. Data including diameter, arterial hyperenhancement, washout, and capsule were reviewed by 2 readers using LI-RADS and LS (range, score 1-5). Inter-reader agreement (IRA), intraclass agreement (ICA), and diagnostic performance were determined by Fleiss, Cohen’s , and logistic regression, respectively.

Results
There were 53 triphasic enhanced computed tomography (CT) and 50 dynamic magnetic resonance (MR) examinations. Overall, IRA was excellent ( = 0.898). IRA was good for arterial hyperenhancement ( = 0.705), washout ( = 0.763), and capsule ( = 0.771) and excellent for diameter ( = 0.981) and tumour embolus ( = 0.927). Overall, ICA between LI-RADS and LS was fair 0.32; ICA was good for scores of 1 ( = 0.682), fair for scores of 2 ( = 0.36), moderate for scores of 5 ( = 0.52), but no agreement was found for scores of 3 ( = –0.059) and 4 ( = –0.022). LIRADS produced relatively high accuracy (87.3% vs. 80%), relatively low sensitivity (84.3% vs. 98%), and significantly higher specificity (89.83% vs. 64.4%) and positive likelihood ratio (+LR: 8.29 vs. 2.75) compared to LS approach.

Conclusions
LI-RADS revealed higher diagnostic accuracy as compared to LS with statistical proof higher specificity and +LR showing its ability to foretell malignancy in high-risk patients. We recommend the practical application of the LI-RADS system in the detection and treatment response monitoring of patients with HCC.

keywords:

hepatocellular carcinoma, LI-RADS, Likert scale, MRI, CT




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