ISSN: 1899-0967
Polish Journal of Radiology
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vol. 84
Original paper

Radiological staging in neuroblastoma: computed tomography or magnetic resonance imaging?

Fatma C. Sarioglu, Muhammet Salman, Handan Guleryuz, Erdener Ozer, Emre Cecen, Dilek Ince, Nur Olgun

© Pol J Radiol 2019; 84: e46-e53
Online publish date: 2019/01/18
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To compare the effectiveness of computed tomography (CT) and magnetic resonance imaging (MRI) in the staging of neuroblastomas according to the International Neuroblastoma Risk Group Staging System (INRGSS).

Material and methods
In this single-centre retrospective study we identified a total of 20 patients under the age of 18 years, who were admitted to our hospital with neuroblastoma between January 2005 and May 2018, and who had both CT and MRI examination. The INRGSS stages of tumours were evaluated by CT scan and MRI. Then, stages of tumours were described according to the INRGSS for CT and MRI, separately. The Spearman rank correlation test was used for statistical analysis. The p-value < 0.05 was considered as statistically significant.

The median age was 11 months, and the age range was one month to nine years. In our results; both MRI and CT were significant in the determination of radiological staging of NBL, p < 0.001 and p = 0.002, respectively. MRI was superior to CT in radiological staging. MRI was also superior for the detection of intraspinal extension, involvement of multiple body compartments, metastatic disease, and bone marrow infiltration. CT was more useful to consider the relationship between tumours and vascular structures.

MRI and CT have high diagnostic accuracy rates in the staging of pre-treatment neuroblastomas. MRI is important in pre-treatment evaluation of neuroblastomas because of the higher detection of metastases as well as the lack of ionising radiation.


children, neuroblastoma, staging, computed tomography, magnetic resonance imaging

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