ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
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1/2021
vol. 86
 
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Chest radiology
abstract:
Original paper

Sensitivity and specificity of chest CT scan based on RT-PCR in COVID-19 diagnosis

Alireza Mirahmadizadeh
1
,
Zahra Pourmontaseri
2
,
Sima Afrashteh
3
,
Mehrnaz Hosseinzadeh
4
,
Jalal Karimi
2
,
Mehdi Sharafi
3, 5

1.
Noncommunicable Diseases Research Center, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran
2.
Department of Infectious Diseases, School of Medicine, Fasa University of Medical Science, Fasa, Iran
3.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran
4.
Research Committee, Fasa University of Medical Sciences, Fasa, Iran
5.
Non-Communicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
© Pol J Radiol 2021; 86: e74-e77
Online publish date: 2021/01/27
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Introduction
COVID-19 is a novel, severely contagious and progressive infection occurring worldwide. The diagnosis of the disease is based on real-time polymerase chain reaction (RT-PCR) and computed tomography (CT) scan, even though they are still controversial methods.

Material and methods
We studied 54 patients with suspected COVID-19 and the two mentioned methods were compared with each other.

Results
Sensitivity and specificity of the abnormal chest CT scan, ground-glass opacity (GGO), consolidation opacity, and both of GGO and consolidation were also surveyed based on RT-PCR. The results showed that RT-PCR assay was negative in 23 (42.6%) patients and positive in 31 (57.4%) cases. Also, the patients with an abnormal chest CT scan comprised 37 (68.5%). The sensitivity and specificity of abnormal CT scan were 78.6% and 42.3%, respectively, based on the RT-PCR method.

Conclusions
Other techniques alongside CT scan and RT-PCR are advocated for accuracy of the COVID-19 diagnosis.

keywords:

RT-PCR, sensitivity and specificity, COVID-19, chest CT scan

 
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