ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
vol. 88
Interventional radiology
Original paper

Finding MRI features to obviate the need of repeat spinal biopsies in clinically suspected persistent or recurrent spinal osteomyelitis

Stephany Barreto
Salil Sharma
Gaurav Cheraya
Amar Swarnkar
Kent Ogden
Rajiv Mangla

SUNY Upstate University Hospital, Syracuse, NY 13210, USA
Mary Imogene Bassett Hospital, Cooperstown, NY 13326, USA
Yale New Haven Health Bridgeport Hospital, USA
© Pol J Radiol 2023; 88: e225-e230
Online publish date: 2023/04/21
View full text Get citation
PlumX metrics:
The aim of this study was to determine magnetic resonance imaging (MRI) features that could help differen­tiate the bone destruction due to persistent/recurrent spine infection from worsening bone destruction due to mechanical factors, which could help obviate the need for repeat spine biopsy.

Material and methods
A retrospective study was performed on selected subjects who were more than 18 years of age, were diagnosed with infectious spondylodiscitis, underwent at least 2 spinal interventions for the diagnosis at the same level, and had MRI prior to each image-guided intervention. Both MRI studies were analysed for vertebral body changes, paravertebral collections, epidural thickening and collections, bone marrow signal changes, loss of vertebral body height, abnormal signal in intervertebral disc, and loss of disc height.

We observed that worsening of changes in paravertebral and epidural soft tissue were statistically more significant predictors of recurrent/persistent spine infection (p < 0.05). However, worsening destruction of vertebral body and intervertebral disc, abnormal vertebral marrow signal changes, and abnormal signal in intervertebral disc did not necessarily indicate worsening infection or recurrence.

In patients of infectious spondylitis with suspected recurrence, the most common and pronounced MRI findings of worsening osseous changes can be deceiving and can result in negative repeat spinal biopsy. Changes in paraspinal and epidural soft tissues are more helpful in identifying the cause of worsening bone destruction. Correlation with clinical examination, inflammatory markers, and observing soft tissue changes on follow-up MRI is a more reliable way to identify patients who may benefit from repeat spine biopsy.


MRI, recurrent infection, spinal biopsy, infectious spondylodiscitis

Quick links
© 2023 Termedia Sp. z o.o.
Developed by Bentus.