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1/2021
vol. 86 Chest radiology
abstract:
Original paper
Sensitivity and specificity of chest CT scan based on RT-PCR in COVID-19 diagnosis
Alireza Mirahmadizadeh
1
,
Zahra Pourmontaseri
2
,
Sima Afrashteh
3
,
Mehrnaz Hosseinzadeh
4
,
Jalal Karimi
2
,
Mehdi Sharafi
3, 5
© Pol J Radiol 2021; 86: e74-e77
Online publish date: 2021/01/27
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Introduction
COVID-19 is a novel, severely contagious and progressive infection occurring worldwide. The diagnosis of the disease is based on real-time polymerase chain reaction (RT-PCR) and computed tomography (CT) scan, even though they are still controversial methods. Material and methods We studied 54 patients with suspected COVID-19 and the two mentioned methods were compared with each other. Results Sensitivity and specificity of the abnormal chest CT scan, ground-glass opacity (GGO), consolidation opacity, and both of GGO and consolidation were also surveyed based on RT-PCR. The results showed that RT-PCR assay was negative in 23 (42.6%) patients and positive in 31 (57.4%) cases. Also, the patients with an abnormal chest CT scan comprised 37 (68.5%). The sensitivity and specificity of abnormal CT scan were 78.6% and 42.3%, respectively, based on the RT-PCR method. Conclusions Other techniques alongside CT scan and RT-PCR are advocated for accuracy of the COVID-19 diagnosis. keywords:
RT-PCR, sensitivity and specificity, COVID-19, chest CT scan |