ISSN: 1899-0967
Polish Journal of Radiology
Established by prof. Zygmunt Grudziński in 1926 Sun
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1/2022
vol. 87
 
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Chest radiology
abstract:
Original paper

Comparative evaluation of severity of COVID-19 pneumonia on computed tomography of the chest in vaccinated and non-vaccinated individuals: an observational study

Manik Mahajan
1
,
Vikrant Gupta
1
,
Mohd Ilyas
2
,
Kulbhushan Gupta
1
,
Parveen Singh
3

1.
Government Medical College, Jammu, Jammu and Kashmir
2.
Steadfast Healthcare Private Limited, Jammu, Jammu and Kashmir
3.
Government Medical College, Kathua, India
Pol J Radiol 2022; 87: e257-e262
Online publish date: 2022/05/11
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Purpose
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus causing an infectious disease, coronavirus disease 2019 (COVID-19). Computed tomography (CT) of the chest plays a significant role in the diagnosis and prognosis of COVID-19 using computed tomography severity scoring (CT-SS). Numerous vaccines are being made available in the world to lessen the effect of the COVID-19 pandemic. The purpose of the current study is to compare the severity of COVID-19 pneumonia using CT-SS in COVID-19-positive vaccinated (Covishield/Oxford-AstraZeneca) and non-vaccinated individuals and to compare the final outcome wherever possible.

Material and methods
This observational study was carried out from March 2021 to April 2021. Forty vaccinated and 40 non-vaccinated RT-PCR-positive COVID-19 patients who underwent CT chest during the 4-12th day of illness formed the material of the study. Semi-quantitative scoring was used, and CT-SS was calculated based on the extent of lobar involvement in all the patients. CT-SS was then compared between the vaccinated and non-vaccinated groups and the results analysed.

Results
CT scans were performed in 80 patients (40 patients each in the vaccinated and non-vaccinated groups). The majority of patients in the vaccinated group had mild (42.5%) and moderate (37.5%) CT-SS while the majority of patients in the non-vaccinated group had moderate (52.5%) and severe (27.5%) CT-SS score on chest CT. Also, no mortality was observed in the vaccinated group, with 2 deaths in the non-vaccinated group.

Conclusions
Covishield vaccine administration reduces the severity of COVID-19 pneumonia as compared to the non-vaccinated group, with a marked reduction in mortality.

keywords:

COVID-19, computed tomography, chest, vaccine, RT-PCR




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