Invasive lobular carcinoma mammographic findings: correlation with age, breast composition, and tumour size
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U.O. Radiologia, ASL Teramo, Italy
Department of Radiological Sciences, Azienda Ospedaliero Universitaria Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy
Department of Radiology, Jinhua Municipal Central Hospital, Jinhua, Zhejiang, China
Submission date: 2020-09-09
Final revision date: 2020-09-29
Acceptance date: 2020-10-06
Publication date: 2021-06-11
Pol J Radiol, 2021; 86: 353-358
The aim of this study was to evaluate mammographic findings associated with invasive lobular carcinoma in different age groups, taking into account breast composition and tumour size.

Material and methods:
A total of 1023 invasive lobular carcinoma preoperative mammograms were evaluated. According to the American College of Radiology Breast Imaging Reporting and Data System, cancer mammographic findings were classified as mass, calcifications, architectural distortion, and asymmetry, and breasts were assessed as dense (C or D breast composition) or non-dense (A or B). The patient cohort was subdivided into 3 age groups (< 50, 50-69, ≥ 70 years of age). In order to make the size and age groups dichotomous variables and to perform multiple regression analysis, a cut-off of 10 mm was chosen for tumour size, and < 50-years-old and 50-69-years-old age groups were grouped together (< 70-years-old age group).

Significant results of multivariate analysis were the association between mass finding and non-dense breasts and size ≥ 10 mm (p < 0.0001), between calcifications, and dense breasts, size < 10 mm and < 70-years-old age group (p < 0.0001), between distortion and < 70-years-old age group (p = 0.0366), and between asymmetry and ≥ 70-years-old age group (p = 0.0090).

Various mammographic findings are differently associated with age group, breast composition, and tumour size.

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