Breast lesions that remain elusive in traditional imaging techniques such as ultrasound and mammography pose a diagnostic challenge. In such cases, magnetic resonance (MR)-guided breast biopsy emerges as a crucial tool for accurate histopathological verification. This article presents a comparative study conducted at 2 centres, exploring the results of MR-guided breast biopsies performed by experienced radiologists, based on inside and external referrals.

Material and methods:
The study involved 228 patients, 120 of whom underwent biopsies at Centre 1, where the same radiologist performed both the qualification and biopsy. The remaining 108 patients were biopsied at Centre 2, based on referrals from different institutions. Uniform examination protocols were adopted at both centres, and all biopsies underwent histopathological verification.

The distribution of lesion types was found to be independent of the apparatus used for biopsies (p = 0.759). Interestingly, Centre 1 exhibited a higher prevalence of infiltrating carcinomas compared to Centre 2 (p = 0.12). Furthermore, the analysis demonstrated a significant variance in the nature of the lesions in relation to breast structure and biopsy centre (p < 0.001).

MR-guided breast biopsy serves as a remarkable tool for verifying lesions that evade detection through conventional imaging methods and physical examinations. The study findings underscore the crucial role of radio­logist experience in determining the efficacy of MR-guided breast biopsies.

Sardanelli F, Giuseppetti GM, Panizza P, Bazzocchi M, Fausto A, Simonetti G, et al. Sensitivity of MRI versus mammography for detecting foci of multifocal, multicentric breast cancer in Fatty and dense breasts using the whole-breast pathologic examination as a gold standard. AJR Am J Roentgenol 2004; 183: 1149-1157.
Thibault F, Dromain C, Breucq C, Balleyguier CS, Malhaire C, Steyaert L, et al. Digital breast tomosynthesis versus mammography and breast ultrasound: a multireader performance study. Eur Radiol 2013; 23: 2441-2449.
Łuczyńska E, Heinze-Paluchowska S, Hendrick E, Dyczek S, Ryś J, Herman K, et al. Comparison between breast MRI and contrast-enhanced spectral mammography. Med Sci Monit 2015; 21: 1358-1367.
Bougias H, Stogiannos N. Breast MRI: where are we currently standing? J Med Imaging Radiat Sci 2022; 53. DOI:
Scaranelo AM. What’s hot in breast MRI. Can Assoc Radiol J 2022; 73: 125-140.
Lee MV, Aharon S, Kim K, Sunn Konstantinoff K, Appleton CM, Stwalley D, et al. Recent trends in screening breast MRI. J Breast Imaging 2021; 4: 39-47.
Papalouka V, Kilburn-Toppin F, Gaskarth M, Gilbert F. MRI-guided breast biopsy: a review of technique, indications, and radiological–pathological correlations. Clin Radiol 2018; 73. DOI:
Adrada BE, Guirguis MS, Hoang T, Spak DA, Rauch GM, Moseley TW. MRI-guided breast biopsy case-based review: essential techniques and approaches to challenging cases. Radiographics 2022; 42. DOI:
Lambert J, Steelandt T, Heywang-Köbrunner SH, Gieraerts K, Van Den Berghe I, Van Ongeval C, et al. Long-term MRI-guided vacuumassisted breast biopsy results of 600 single-center procedures. Eur Radiol 2021; 31. DOI:
Nida BA, Rooney TB, Miller MM. Utility of MRI-directed contrast-enhanced mammography for biopsy planning for suspicious MRI-detected breast lesions. Am J Roentgenol 2023; 220. DOI:
He Y, Zhou J, Liu X, Wei Y, Ye S, Miao H, et al. Evaluation of association between menstrual cycle timing and quantitative background parenchymal enhancement on breast MRI in premenopausal women. Clin Breast Cancer 2023; 23: e451-e457.e1. DOI:
American College of Radiology. ACR BI-RADS® Atlas 5 Edition Changes. 2014. Available at:
Journals System - logo
Scroll to top